I am a clinical academic psychiatrist (on the GMC Specialist Register for Old Age and General Adult Psychiatry) with a focus on the development of treatments for neuropsychiatric disorders. My experience spans the key components of neuroscience clinical trial methodology: conduct of proof-of-concept biomarker-based clinical trials in surrogate populations, testing of repurposed compounds, development of stratification and efficacy biomarkers and creation of infrastructure for large-scale stratified recruitment into neuroscience experimental medicine studies and clinical trials. I have a particular interest in the potential value of digital and wearable technologies to detect preclinical dementia and have been a medical advisor and investigator with start-ups developing digital solutions for the pre- and post-diagnostic space.