Dr. Nimer has been studying the transcriptional regulation of normal and malignant hematopoiesis for decades, with the aim of understanding how the normal processes of stem cell self-renewal and differentiation are regulated and how these processes are aberrant in the myeloid malignancies. Overall, his lab has focused on defining genes that contribute to the development and progression of myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) and on identifying novel ways to target hematologic cancers and make them more responsive to treatment.As a physician-scientist, Dr. Nimer has cared for patients with MDS, AML, multiple myeloma, and lymphoma for over three decades. This melding of clinical studies and care, with both basic laboratory and translational studies, reflects the fundamental focus of his career.Since coming to the University of Miami-Miller School of Medicine in 2012 and assuming the Directorship of the Sylvester Comprehensive Cancer Center, the center received the prestigious National Cancer Institute designation in July 2019. Sylvester is the only cancer center in South Florida to achieve this designation and the second in the state of Florida. Dr. Nimer is currently supported by two NCI R01 grants and a Leukemia and Lymphoma Society (LLS) multi-project Specialized Center of Research (SCOR) award. In November 2019, Dr. Nimer was named the inaugural Oscar de la Renta Endowed Chair in Cancer Research. In November 2021, Dr. Nimer assumed the role of Executive Dean for Research for the Miller School of Medicine, and in May 2022, he assumed a secondary appointment as Professor of Chemical, Environmental & Materials Engineering.Prior to his arrival at the University of Miami-Miller School of Medicine, Dr. Nimer was at Memorial Sloan-Kettering Cancer Center in New York for nearly 20 years, where he held the Alfred P. Sloan Chair and served as Head of the Division of Hematologic Oncology, Vice Chairman for Faculty Development, and Chief of the Hematology Service. He was also a Professor of Medicine and Pharmacology at Weill Medical College of Cornell University. Dr. Nimer has been elected to the American Society of Clinical Investigators and the Association of American Physicians. He is a Fellow of the American College of Physicians and serves on the editorial board of several medical journals. In April 2021, Dr. Nimer was inducted into the Academy of Science, Engineering, and Medicine of Florida. Dr. Nimer is also the Chairman of the Myelodysplastic Syndrome Foundation, and the Chairman of the Medical Advisory Board of Gabrielle's Angel Foundation for Cancer Research.