Dr. Antonelli was born and raised in California where she graduated with a degree in Biology with Honors from the University of California at Santa Cruz in 1990. She attended the University of North Carolina School of Medicine in Chapel Hill, NC where she graduated with Honors in 1995. She completed her residency in Obstetrics and Gynecology at New Hanover Regional Medical Center in 1999 where she served as administrative chief resident in her final year. She was employed by Azalea Gynecology until 2014 when she made the decision to open her own solo private gynecology practice.