Jean-Philippe ROCHER is a medicinal chemist with more than 20 years of experience in Drug Discovery within the pharmaceutical industry and Biotech companies with record of accomplishment (4 NCEs with PoC Phase IIa,, numerous preclinical). He has experience in a wide set of target types and therapeutic areas in particular in allosteric modulation approaches. Besides the implementation and the management of chemistry platform specialized in the delivery of small molecule clinical candidates, he is managing IP. He has been instrumental in providing scientific support for research collaboration deals and funding through VCs. Dr Rocher has played important scientific and management role in European, US and Japanese companies. Specialties Design and selection of clinical candidates; management of chemistry departments, paying attention to human factors, scientific quality and delivery;. project management from hit to clinical candidate; chemistry from early discovery to CMC (internally or through collaborations: academic; CROs); building and management of corporate screening libraries including fragments; collaborations and integrated drug discovery approaches through CROs (worldwide). Extensive experience in hit validation and lead optimization. Targets: enzymes/nuclear receptors/kinases/GPCRs ; allosteric modulation Therapeutic fields: immunology, CNS, oncology, dermatology Intellectual propertry (writing, prosecution, portfolio management and strategy). Communication: scientifc & business; due diligence, consulting.
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