Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin degludec is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. Liraglutide is similar to a hormone that occurs naturally in the body and helps control blood sugar, insulin levels, and digestion. Insulin degludec and liraglutide is a combination medicine used to lower blood sugar in adults with type 2 diabetes mellitus. This medicine should be used together with diet and exercise. Insulin degludec and liraglutide is usually given when your blood sugar levels have not been well controlled by using other medications. Insulin degludec and liraglutide is not for people with type 1 diabetes. Insulin degludec and liraglutide may also be used for purposes not listed in this medication guide.